Compound name
KISS1-543
Protein family
GPCR
Target name
KISS1R
CG-Set
GPCR set
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0001072a
SMILES
CC(C[C@H](NC(NNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@H](N)Cc1ccc(O)cc1)=O)CC2=CC=NC=C2)=O)CC(N)=O)=O)CO)=O)Cc3ccccc3)=O)=O)C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(NCC)=O)=O)CCCNC(NC)=N)=O)C
InChIKey
KSPGBAVXLLOLOZ-FIWWHSBNSA-N
NCBI gene ID
84634
UniProt ID
Q969F8
Synonyms
HOT7T175, AXOR12
Mode of action
Negative control for KISS1-305
Selectivity platform
GPCR panel (PDSP screen)
Selectivity platform number of targets
45
Selectivity remarks
Screened at 1 µM, closest target as % of inhibition: CHRM2 (40.7%)
Selectivity Source Knowledge
https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/KISS1-305