1. Chemogenomics
2. ADRB1

ADRB1

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

153

285

P08588

ADRB1_HUMAN

adrenoceptor beta 1

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000377a

CIMATEROL

CC(C)NCC(O)C1=CC(C#N)=C(N)C=C1

BUXRLJCGHZZYNE-UHFFFAOYSA-N

Agonist

ADRB1

Yes

Yes

No

Yes

EUB0000418aCl

PROPRANOLOL

CC(C)NCC(O)COC1=C2C=CC=CC2=CC=C1

ZMRUPTIKESYGQW-UHFFFAOYSA-N

Antagonist

ADRB1

,

ADRB2

Yes

Yes

No

Yes

EUB0000419aCl

BETAXOLOL

CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1

CHDPSNLJFOQTRK-UHFFFAOYSA-N

Antagonist

ADRB1

Yes

Yes

Yes

Yes

EUB0000420aCl

CGP-12177

CC(C)(C)NCC(O)COC1=C2NC(=O)NC2=CC=C1

YQVFCYCTITZLSX-UHFFFAOYSA-N

Antagonist

ADRB1

,

ADRB2

Yes

Yes

No

Yes

EUB0000450a

TIMOLOL

CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1

BLJRIMJGRPQVNF-JTQLQIEISA-N

Antagonist

ADRB1

,

ADRB2

Yes

Yes

Yes

Yes

EUB0000499a

INDACATEROL

CCC1=CC2=C(CC(C2)NC[C@H](O)C2=C3C=CC(=O)NC3=C(O)C=C2)C=C1CC

QZZUEBNBZAPZLX-QFIPXVFZSA-N

Agonist

ADRB1

,

ADRB2

Yes

Yes

Yes

Yes

EUB0000538a

ICI-89406

OC(CNCCNC(=O)NC1=CC=CC=C1)COC1=CC=CC=C1C#N

HTLWRKRZKFAAAH-UHFFFAOYSA-N

Antagonist

ADRB1

Yes

Yes

No

Yes