1. Chemogenomics
  2. CCR2

CCR2

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family
729230
1603
P41597
CCR2_HUMAN
C-C motif chemokine receptor 2
GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available
EUB0000465a
BMS CCR2 22
Chemical structure of compound BMS CCR2 22
CSC1=CC=C(C=C1)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)CNC(=O)C1=C(NC(=O)NC(C)C)C=CC(=C1)C(F)(F)F
IBPXYDUJQWENPM-XZOQPEGZSA-N
Antagonist
CCR2
Yes
Yes
No
Yes
EUB0000474aCl
PLERIXAFOR
Chemical structure of compound PLERIXAFOR
C(N1CCCNCCNCCCNCC1)C1=CC=C(CN2CCCNCCNCCCNCC2)C=C1
VZVSLNRDUPMOSZ-UHFFFAOYSA-N
Antagonist
CCR2
Yes
Yes
No
Yes
EUB0000479a
MK-0812
Chemical structure of compound MK-0812
CO[C@@H]1COCC[C@@H]1N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1CCC2=C(C1)C=C(C=N2)C(F)(F)F
MTMDXAIUENDNDL-RJSMDTJLSA-N
Antagonist
CCR2
Yes
Yes
No
Yes