1. Chemogenomics
  2. INSR

INSR

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family
3643
6091
P06213
INSR_HUMAN
Insulin receptor
Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available
EUB0000601a
GSK1904529A
Chemical structure of compound GSK1904529A
O=C(NC1=C(F)C=CC=C1F)C2=CC(C3=C(C4=NC(NC5=C(OC)C=C(N6CCC(N7CCN(S(C)(=O)=O)CC7)CC6)C(CC)=C5)=NC=C4)N8C=CC=CC8=N3)=CC=C2OC
MOSKATHMXWSZTQ-UHFFFAOYSA-N
IGF1R
,
INSR
Yes
Yes
No
Yes
EUB0000614a
Linsitinib
Chemical structure of compound Linsitinib
NC1=NC=CN2C1=C(C3=CC(N=C(C4=CC=CC=C4)C=C5)=C5C=C3)N=C2[C@H]6C[C@@](C)(O)C6
PKCDDUHJAFVJJB-VLZXCDOPSA-N
inhibitor
IGF1R
,
INSR
,
INSRR
Yes
Yes
No
Yes
EUB0000670a
BMS-754807
Chemical structure of compound BMS-754807
C[C@]1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F
LQVXSNNAFNGRAH-QHCPKHFHSA-N
IGF1R
,
INSR
Yes
Yes
Yes
Yes