1. Chemogenomics
2. MMP12

MMP12

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

4321

7158

P39900

MMP12_HUMAN

matrix metallopeptidase 12

MMP

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000725a

BAY-694

O=C(C1=C(N=N2)C=CC=C1)N2C[C@H]([C@H]3C(O)=O)CC[C@H]3C(C(C=C4)=CC=C4OCCC5CCOCC5)=O

ZGBAPSHWPBXEKN-QFZRFWILSA-N

Neg Ctrl (BAY-7598)

MMP12

Yes

Yes

No

Yes

EUB0000728a

BAY-7598

O=C(C1=C(N=N2)C=CC=C1)N2C[C@@H]([C@@H]3C(O)=O)CC[C@@H]3C(C(C=C4)=CC=C4OCCC5CCOCC5)=O

ZGBAPSHWPBXEKN-OPHFCASCSA-N

MMP12

Yes

Yes

No

Yes