1. Chemogenomics
2. RXRG

RXRG

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

6258

10479

P48443

RXRG_HUMAN

retinoid X receptor gamma

Nuclear receptor

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000181b

bexarotene

C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C

NAVMQTYZDKMPEU-UHFFFAOYSA-N

RXRA

,

RXRB

,

RXRG

Yes

Yes

No

Yes

EUB0000187b

JP147

CN(c1cc(C(F)(F)F)nc(OCCC(=O)O)n1)c1cccc2c1CCC2

YMSJOQCCWIPKGF-UHFFFAOYSA-N

RXRA

,

RXRB

,

RXRG

Yes

Yes

Yes

Yes

EUB0000553a

DC 271

CC(N1CCC(C)(C2=CC(C#CC3=CC=C(C(O)=O)C=C3)=CC=C12)C)C

OCMSZODRCJAGHL-UHFFFAOYSA-N

RXRA

,

RXRB

,

RXRG

Yes

Yes

Yes

Yes

EUB0000554a

LG 101506

CC(C)(C)C1=CC(/C(C)=C\C=C\C(C)=C\C(O)=O)=C(OCC(F)F)C(C(C)(C)C)=C1

BHIBZAZKKARFIM-XRYBSMBUSA-N

RXRA

,

RXRB

,

RXRG

Yes

Yes

No

Yes

EUB0000577a

LG 100268

CC1=CC2=C(C=C1C3(CC3)C4=NC=C(C=C4)C(=O)O)C(CCC2(C)C)(C)C

SLXTWXQUEZSSTJ-UHFFFAOYSA-N

RXRA

,

RXRB

,

RXRG

Yes

Yes

No

Yes