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Chemogenomics
ABL2

ABL2

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

ABL2_HUMAN

Abelson tyrosine-protein kinase 2

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000593a

Nilotinib

Cc1ncn(c1)c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)c3cccnc3)c2)cc(c1)C(F)(F)F

HHZIURLSWUIHRB-UHFFFAOYSA-N

ABL1

ABL2

Yes

EUB0000875a

GNF2

NC(C1=CC(C2=NC=NC(NC3=CC=C(OC(F)(F)F)C=C3)=C2)=CC=C1)=O

WEVYNIUIFUYDGI-UHFFFAOYSA-N

allosteric

ABL1

ABL2

Yes

The EUbOPEN project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 875510. This Joint Undertaking receives support from the European Union's Horizon 2020 research and innovation programme, EFPIA companies and Associated Partners: KTH, OICR, Diamond and McGill. This communication reflects the views of the authors and neither IMI nor the European Union, EFPIA or any Associated Partners are liable for any use that may be made of the information contained herein.

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