1. Chemogenomics
2. ADORA2A

ADORA2A

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

135

263

P29274

AA2AR_HUMAN

adenosine A2a receptor

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000397a

MRS-1220

ClC1=CC=C2N=C(NC(=O)CC3=CC=CC=C3)N3N=C(N=C3C2=C1)C1=CC=CO1

TWWFAXQOKNBUCR-UHFFFAOYSA-N

Antagonist

ADORA2A

,

ADORA3

Yes

Yes

No

Yes

EUB0000417a

ZM-241385

NC1=NC(NCCC2=CC=C(O)C=C2)=NC2=NC(=NN12)C1=CC=CO1

PWTBZOIUWZOPFT-UHFFFAOYSA-N

Antagonist

ADORA2A

Yes

Yes

No

Yes

EUB0000470a

TC-G 1004

COC1CCN(CC1)C1=NC(=CC=C1)C1=CC(NC(C)=O)=NC(=N1)N1N=C(C)C=C1C

JENSDTKXNVHSSN-UHFFFAOYSA-N

Antagonist

ADORA2A

Yes

Yes

No

Yes