1. Chemogenomics
2. ADORA3

ADORA3

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

140

268

P0DMS8

AA3R_HUMAN

adenosine A3 receptor

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000397a

MRS-1220

ClC1=CC=C2N=C(NC(=O)CC3=CC=CC=C3)N3N=C(N=C3C2=C1)C1=CC=CO1

TWWFAXQOKNBUCR-UHFFFAOYSA-N

Antagonist

ADORA2A

,

ADORA3

Yes

Yes

No

Yes

EUB0000433aCl

PSB-11

CC[C@@H]1CN2C(=N1)C1=C(N=C(N1)C1=CC=CC=C1)N(C)C2=O

JAUSHKIWPLHBCN-RFVHGSKJSA-N

Antagonist

ADORA3

Yes

Yes

No

Yes

EUB0000434a

HEMADO

CCCCC#CC1=NC(NC)=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=N1

KOCIMZNSNPOGOP-IWCJZZDYSA-N

Agonist

ADORA3

Yes

Yes

No

Yes