1. Chemogenomics
  2. ADRA1D

ADRA1D

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family
146
280
P25100
ADA1D_HUMAN
adrenoceptor alpha 1D
GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available
EUB0000300bCl
(R)-9s
Chemical structure of compound (R)-9s
C[C@@H](c1cccc(CN)c1)n1cc(Cl)cc(C(N)=O)c1=N.Cl
PIRKVXKOMRREFI-FVGYRXGTSA-N
ADRA1D
Yes
Yes
No
Yes
EUB0000341aCl
(S)-9s
Chemical structure of compound (S)-9s
C[C@@H](C1=CC=CC(C#N)=C1)N2C=C(C=C(C2=N)C(N)=O)Cl.[H]Cl
XUCZRJDRBBJCTE-FVGYRXGTSA-N
Neg Ctrl ((R)-9s)
ADRA1D
Yes
Yes
No
Yes
EUB0000381a
SILODOSIN
Chemical structure of compound SILODOSIN
C[C@H](CC1=CC2=C(N(CCCO)CC2)C(=C1)C(N)=O)NCCOC1=C(OCC(F)(F)F)C=CC=C1
PNCPYILNMDWPEY-QGZVFWFLSA-N
Antagonist
ADRA1A
,
ADRA1D
Yes
Yes
No
Yes
EUB0000404aCl
DEXMEDETOMIDINE
Chemical structure of compound DEXMEDETOMIDINE
C[C@H](C1=CN=CN1)C1=C(C)C(C)=CC=C1
VPNGEIHDPSLNMU-MERQFXBCSA-N
Agonist
ADRA1D
Yes
Yes
No
Yes