1. Chemogenomics
2. AVPR2

AVPR2

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

554

897

P30518

V2R_HUMAN

arginine vasopressin receptor 2

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000413a

TOLVAPTAN

CC1=C(C=CC=C1)C(=O)NC1=CC(C)=C(C=C1)C(=O)N1CCCC(O)C2=C1C=CC(Cl)=C2

GYHCTFXIZSNGJT-UHFFFAOYSA-N

Antagonist

AVPR2

Yes

Yes

No

Yes

EUB0000446a

TC OT 39

CN1N=CC2=C1NC1=CC=CC=C1N(C2)C(=O)C1=CC(C)=C(CNC(=O)N2CCC[C@H]2C(=S)N2CCCN(C)CC2)C=C1

KSNHHKZYKYNBEI-NDEPHWFRSA-N

Partial agonist

AVPR1A

,

AVPR2

,

OXTR

Yes

Yes

No

Yes