1. Chemogenomics
2. CLK3

CLK3

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

1198

2071

P49761

CLK3_HUMAN

Dual specificity protein kinase CLK3

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000321b

T3-CLK

CN1CCN(C(=O)C(C)(C)c2ccc(C(=O)Nc3cn4cc(-c5ccncc5)ccc4n3)cc2)CC1

IEFFSHLHNYVSEF-UHFFFAOYSA-N

CLK1

,

CLK2

,

CLK3

,

CLK4

Yes

Yes

Yes

Yes

EUB0000705a

T3-CLK-N

CN1CCN(C(C(C)(C2=CC=C(C(NC3=CN4C=C(C5=CC(C(C)(C)C)=CC(C(C)(C)C)=C5)C=CC4=N3)=O)C=C2)C)=O)CC1

BNTGVINQADRYBE-UHFFFAOYSA-N

Neg Ctrl (T3-CLK)

CLK1

,

CLK2

,

CLK3

,

CLK4

Yes

Yes

No

Yes