1. Chemogenomics
2. CLK4

CLK4

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

57396

13659

Q9HAZ1

CLK4_HUMAN

Dual specificity protein kinase CLK4

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000009b

MU140

Cn1cc(-c2ccc3occ(-c4ccccc4-c4ccccc4)c3n2)cn1

QSBNKGGRYOLZND-UHFFFAOYSA-N

Neg Ctrl (MU1210)

CLK1

,

CLK2

,

CLK4

Yes

Yes

No

Yes

EUB0000321b

T3-CLK

CN1CCN(C(=O)C(C)(C)c2ccc(C(=O)Nc3cn4cc(-c5ccncc5)ccc4n3)cc2)CC1

IEFFSHLHNYVSEF-UHFFFAOYSA-N

CLK1

,

CLK2

,

CLK3

,

CLK4

Yes

Yes

Yes

Yes

EUB0000705a

T3-CLK-N

CN1CCN(C(C(C)(C2=CC=C(C(NC3=CN4C=C(C5=CC(C(C)(C)C)=CC(C(C)(C)C)=C5)C=CC4=N3)=O)C=C2)C)=O)CC1

BNTGVINQADRYBE-UHFFFAOYSA-N

Neg Ctrl (T3-CLK)

CLK1

,

CLK2

,

CLK3

,

CLK4

Yes

Yes

No

Yes

EUB0000724a

SGC-CLK-1 (UNC-CAF-170 )

COC1=NN2N=CC(C3=NC(NC4=CC(C(F)(F)F)=CC(OC)=C4)=NC=C3)=C2C=C1

GJYVLTPTDBQQCY-UHFFFAOYSA-N

CLK1

,

CLK2

,

CLK4

Yes

Yes

Yes

Yes