1. Chemogenomics
2. HCRTR1

HCRTR1

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

3061

4848

O43613

OX1R_HUMAN

hypocretin receptor 1

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000439a

SB-408124

CN(C)C1=CC=C(NC(=O)NC2=C3C=C(F)C=C(F)C3=NC(C)=C2)C=C1

JTARFZSNUAGHRB-UHFFFAOYSA-N

Antagonist

HCRTR1

,

HTR2B

Yes

Yes

No

Yes

EUB0000440a

SB 674042

CC1=NC(C(=O)N2CCC[C@H]2CC2=NN=C(O2)C2=CC=CC=C2)=C(S1)C1=CC=CC=C1F

HYBZWVLPALMACV-KRWDZBQOSA-N

Antagonist

HCRTR1

Yes

Yes

No

Yes