1. Chemogenomics
2. HTR2B

HTR2B

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

3357

5294

P41595

5HT2B_HUMAN

5-hydroxytryptamine receptor 2B

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000439a

SB-408124

CN(C)C1=CC=C(NC(=O)NC2=C3C=C(F)C=C(F)C3=NC(C)=C2)C=C1

JTARFZSNUAGHRB-UHFFFAOYSA-N

Antagonist

HCRTR1

,

HTR2B

Yes

Yes

No

Yes

EUB0000456aCl

CP 809,101

ClC1=CC(COC2=NC(=CN=C2)N2CCNCC2)=CC=C1

NMUNRTCTDLORDR-UHFFFAOYSA-N

Agonist

HTR2A

,

HTR2B

,

HTR2C

Yes

Yes

No

Yes

EUB0000486aCl

AZELASTINE

CN1CCCC(CC1)N1N=C(CC2=CC=C(Cl)C=C2)C2=CC=CC=C2C1=O

YEJAJYAHJQIWNU-UHFFFAOYSA-N

Antagonist

HRH1

,

HTR2B

Yes

Yes

Yes

Yes