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Chemogenomics
HTR1B

HTR1B

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

3351

5287

P28222

5HT1B_HUMAN

5-hydroxytryptamine receptor 1B

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000409a

SB-224289

CN1CCC2(COC3=C2C=C2N(CCC2=C3)C(=O)C2=CC=C(C=C2)C2=CC=C(C=C2C)C2=NOC(C)=N2)CC1

ATQMRMGXINTJHV-UHFFFAOYSA-N

Inverse agonist

HTR1B

Yes

EUB0000410aCl

Oxymetazoline

CC1=CC(=C(O)C(C)=C1CC1=NCCN1)C(C)(C)C

BEEDODBODQVSIM-UHFFFAOYSA-N

Agonist

ADRA2A

ADRA2C

HTR1B

HTR1D

Yes

The EUbOPEN project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 875510. This Joint Undertaking receives support from the European Union's Horizon 2020 research and innovation programme, EFPIA companies and Associated Partners: KTH, OICR, Diamond and McGill. This communication reflects the views of the authors and neither IMI nor the European Union, EFPIA or any Associated Partners are liable for any use that may be made of the information contained herein.

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