1. Chemogenomics
2. MAPK7

MAPK7

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

5598

6880

Q13164

MK07_HUMAN

Mitogen-activated protein kinase 7

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000122b

XMD8-92

OC1CCN(C2=CC(OCC)=C(NC3=NC=C(N(C)C(C(C=CC=C4)=C4N5C)=O)C5=N3)C=C2)CC1

QAPAJIZPZGWAND-UHFFFAOYSA-N

MAPK7

Yes

Yes

No

Yes

EUB0000250b

BAY-885

CN1CCN(c2cnc3c(C4CCN(C(=O)c5ccc(OC(F)(F)F)cc5N)CC4)ncnc3c2)CC1

QXURFIGBRGWPQD-UHFFFAOYSA-N

MAPK7

Yes

Yes

No

Yes

EUB0000628a

XMD8-85

CN1CCN(C2=CC(OC)=C(NC3=NC=C(N(C)C(C(C=CC=C4)=C4N5C)=O)C5=N3)C=C2)CC1

DDTPGANIPBKTNU-UHFFFAOYSA-N

LRRK2

,

MAPK7

Yes

Yes

Yes

Yes

EUB0000687a

XMD17-109

CN1CCN(C2CCN(C(C3=CC(OCC)=C(NC4=NC=C(N(C)C(C(C=CC=C5)=C5N6C7CCCC7)=O)C6=N4)C=C3)=O)CC2)CC1

XVBGRTMNFNMINE-UHFFFAOYSA-N

MAPK7

Yes

Yes

Yes

Yes

EUB0000708a

BAY-693

CC1=NC(C=C(N2CCN(CC2)C)C=N3)=C3C(C4CCN(C(C5=CC=C(OC(F)(F)F)C=C5N)=O)CC4)=N1

AROOGPVJRFLMEV-UHFFFAOYSA-N

Neg Ctrl(BAY-885)

MAPK7

Yes

Yes

No

Yes