1. Chemogenomics
2. PLK3

PLK3

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

1263

2154

Q9H4B4

PLK3_HUMAN

Serine/threonine-protein kinase PLK3

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000669a

Volasertib

CC[C@@H]1C(N(C)C2=CN=C(NC3=C(OC)C=C(C(N[C@@H]4CC[C@@H](N5CCN(CC6CC6)CC5)CC4)=O)C=C3)N=C2N1C(C)C)=O

SXNJFOWDRLKDSF-STROYTFGSA-N

PLK1

,

PLK2

,

PLK3

Yes

Yes

No

Yes

EUB0000698a

GW843682X

COC1=C(OC)C=C(N=CN2C3=CC(OCC4=CC=CC=C4C(F)(F)F)=C(C(N)=O)S3)C2=C1

JSKUWFIZUALZLX-UHFFFAOYSA-N

PLK1

,

PLK3

Yes

Yes

Yes

Yes