1. Chemogenomics
2. RARA

RARA

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

5914

9864

P10276

RARA_HUMAN

retinoic acid receptor alpha

Nuclear receptor

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000563a

tazarotene

CCOC(=O)C1=CN=C(C=C1)C#CC2=CC3=C(C=C2)SCCC3(C)C

OGQICQVSFDPSEI-UHFFFAOYSA-N

RARA

,

RARB

,

RARG

Yes

Yes

No

Yes

EUB0000565a

BMS753

CC1(C2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)C(C1=O)(C)C)C

KFBPBWUZXBYJDG-UHFFFAOYSA-N

RARA

Yes

Yes

No

No

EUB0000566a

tamibarotene

CC1(CCC(C2=C1C=CC(=C2)NC(=O)C3=CC=C(C=C3)C(=O)O)(C)C)C

MUTNCGKQJGXKEM-UHFFFAOYSA-N

RARA

Yes

Yes

No

Yes

EUB0000567a

Ro 40-6055

CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C

SZWKGOZKRMMLAJ-UHFFFAOYSA-N

RARA

,

RARB

,

RARG

Yes

Yes

No

Yes