1. Chemogenomics
2. RARG

RARG

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

5916

9866

P13631

RARG_HUMAN

retinoic acid receptor gamma

Nuclear receptor

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000563a

tazarotene

CCOC(=O)C1=CN=C(C=C1)C#CC2=CC3=C(C=C2)SCCC3(C)C

OGQICQVSFDPSEI-UHFFFAOYSA-N

RARA

,

RARB

,

RARG

Yes

Yes

No

Yes

EUB0000564a

adapalene

COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5

LZCDAPDGXCYOEH-UHFFFAOYSA-N

RARB

,

RARG

Yes

Yes

No

Yes

EUB0000567a

Ro 40-6055

CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C

SZWKGOZKRMMLAJ-UHFFFAOYSA-N

RARA

,

RARB

,

RARG

Yes

Yes

No

Yes

EUB0000568a

AHPN

C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC6=C(C=C5)C=C(C=C6)C(=O)O)O

LDGIHZJOIQSHPB-UHFFFAOYSA-N

RARG

Yes

Yes

Yes

Yes