1. Chemogenomics
  2. BRD4@BD1

BRD4@BD1

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family
23476
13575
O60885
BRD4_HUMAN
bromodomain containing 4
Bromodomain

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available
EUB0000102c
I-BET151 (GSK1210151A)
Chemical structure of compound I-BET151 (GSK1210151A)
COc1cc2c(cc1-c1c(C)noc1C)ncc1nc(O)n([C@H](C)c3ccccn3)c12
VUVUVNZRUGEAHB-CYBMUJFWSA-N
BRD2@BD1
,
BRD2@BD2
,
BRD3@BD1
,
BRD3@BD2
,
BRD4@BD1
,
BRD4@BD2
,
BRDT@BD1
,
BRDT@BD2
Yes
Yes
No
No
EUB0000169b
BI-2536
Chemical structure of compound BI-2536
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1
XQVVPGYIWAGRNI-JOCHJYFZSA-N
BRD4@BD1
,
PLK1
Yes
Yes
No
Yes
EUB0000330a
(+)-JQ1
Chemical structure of compound (+)-JQ1
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(CC(=O)OC(C)(C)C)c1nnc(C)n1-2
DNVXATUJJDPFDM-KRWDZBQOSA-N
BRD2@BD1
,
BRD2@BD2
,
BRD3@BD1
,
BRD3@BD2
,
BRD4@BD1
,
BRD4@BD2
,
BRDT@BD1
,
BRDT@BD2
Yes
Yes
No
No