1. Chemogenomics
2. MAP4K2

MAP4K2

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

5871

6864

Q12851

M4K2_HUMAN

Mitogen-activated protein kinase kinase kinase kinase 2

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000020bCl

NG 25 (hydrochloride hydrate)

CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(OC4=CC=NC5=C4C=CN5)=C(C)C=C3)=O)C=C2)CC1.Cl.Cl.Cl.O

MTCWJLFLTFRXLX-UHFFFAOYSA-N

ABL1

,

CSK

,

FER

,

LYN

,

MAP3K7

,

MAP4K2

,

MAPK14

,

SRC

Yes

Yes

No

No

EUB0000238b

TL4-12

CNc1cc(Oc2cc(C(=O)Nc3cc(N4CCN(C)CC4)cc(C(F)(F)F)c3)ccc2C)ncn1

HXKJJIMUMNPQQY-UHFFFAOYSA-N

MAP4K2

Yes

Yes

Yes

Yes