1. Chemogenomics
2. SRC

SRC

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

6714

11283

P12931

SRC_HUMAN

Proto-oncogene tyrosine-protein kinase Src

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000020bCl

NG 25 (hydrochloride hydrate)

CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(OC4=CC=NC5=C4C=CN5)=C(C)C=C3)=O)C=C2)CC1.Cl.Cl.Cl.O

MTCWJLFLTFRXLX-UHFFFAOYSA-N

ABL1

,

CSK

,

FER

,

LYN

,

MAP3K7

,

MAP4K2

,

MAPK14

,

SRC

Yes

Yes

No

No

EUB0000662a

Saracatinib

ClC1=CC=C2C(OCO2)=C1NC3=NC=NC4=C3C(OC5CCOCC5)=CC(OCCN6CCN(C)CC6)=C4

OUKYUETWWIPKQR-UHFFFAOYSA-N

SRC

Yes

Yes

Yes

No

EUB0000683a

Tirbanibulin

O=C(CC1=NC=C(C2=CC=C(OCCN3CCOCC3)C=C2)C=C1)NCC4=CC=CC=C4

HUNGUWOZPQBXGX-UHFFFAOYSA-N

SRC

Yes

Yes

Yes

No