1. Chemogenomics
2. DRD3

DRD3

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

1814

3024

P35462

DRD3_HUMAN

dopamine receptor D3

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000394a

L-741,626

OC1(CCN(CC2=CNC3=CC=CC=C23)CC1)C1=CC=C(Cl)C=C1

LLBLNMUONVVVPG-UHFFFAOYSA-N

Antagonist

DRD2

,

DRD3

Yes

Yes

Yes

Yes

EUB0000443aCl

DIFLUOROBENZTROPINE

CN1C2CCC1CC(C2)OC(C1=CC=C(F)C=C1)C1=CC=C(F)C=C1

YOORVSGDAHWVMC-UHFFFAOYSA-N

Antagonist

CHRM1

,

DRD3

Yes

Yes

Yes

Yes

EUB0000493aCl

CARIPRAZINE

CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)C2=C(Cl)C(Cl)=CC=C2)CC1

GPPJWWMREQHLQT-BHQIMSFRSA-N

Antagonist

DRD2

,

DRD3

,

HTR1A

Yes

Yes

Yes

Yes