1. Chemogenomics
  2. FLT3

FLT3

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family
2322
3765
P36888
FLT3_HUMAN
Receptor-type tyrosine-protein kinase FLT3
Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available
EUB0000176b
Brigatinib (AP-26113)
Chemical structure of compound Brigatinib (AP-26113)
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1
AILRADAXUVEEIR-UHFFFAOYSA-N
ALK
,
FLT3
,
IGF1R
,
ROS1
Yes
Yes
No
Yes
EUB0000681a
Pacritinib
Chemical structure of compound Pacritinib
C12=C(OCCN3CCCC3)C=CC(/N=C4N=CC=C(C5=CC=CC(COC/C=C/COC2)=C5)N/4)=C1
HWXVIOGONBBTBY-ONEGZZNKSA-N
FLT3
,
JAK2@kinase 1
,
TYK2@kinase 1
Yes
Yes
Yes
Yes