1. Chemogenomics
2. HTR6

HTR6

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

3362

5301

P50406

5HT6R_HUMAN

5-hydroxytryptamine receptor 6

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000416aCl

SB 271046

COC1=CC=C(NS(=O)(=O)C2=C(C)C3=CC(Cl)=CC=C3S2)C=C1N1CCNCC1

RMXZRJYGJMSDQK-UHFFFAOYSA-N

Antagonist

HTR6

Yes

Yes

Yes

Yes

EUB0000480a

LATREPIRDINE

CN1CCC2=C(C1)C1=CC(C)=CC=C1N2CCC1=CC=C(C)N=C1

JNODQFNWMXFMEV-UHFFFAOYSA-N

Antagonist

ADRA1A

,

ADRA2A

,

HRH1

,

HTR2A

,

HTR2C

,

HTR6

,

HTR7

Yes

Yes

Yes

Yes